Document Detail


A case of chronic hepatitis C developing insulin-dependent diabetes, thyroid autoimmunity and stiff-person syndrome as complications of interferon therapy.
MedLine Citation:
PMID:  20541278     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe the case of a 66-year-old man with chronic hepatitis C who developed type 1 diabetes mellitus (T1DM) and thyroid autoimmunity during Interferon alpha (INFalpha) therapy and then stiff-person syndrome (SPS). This is the first reported case in which SPS has appeared as complication of IFNalpha therapy.
Authors:
G Scavone; F Zaccardi; A Manto; S Caputo; D Pitocco; G Ghirlanda
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-06-11
Journal Detail:
Title:  Diabetes research and clinical practice     Volume:  89     ISSN:  1872-8227     ISO Abbreviation:  Diabetes Res. Clin. Pract.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-27     Completed Date:  2010-11-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508335     Medline TA:  Diabetes Res Clin Pract     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  e36-8     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Department of Internal Medicine, Catholic University School of Medicine, Rome, Italy. jekoide80@yahoo.it
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MeSH Terms
Descriptor/Qualifier:
Aged
Autoimmunity / drug effects*
Diabetes Mellitus, Type 1 / chemically induced*
Hepatitis C, Chronic / drug therapy*
Humans
Interferon-alpha / adverse effects*,  therapeutic use*
Male
Stiff-Person Syndrome / chemically induced*
Thyroid Gland / immunology*,  pathology
Chemical
Reg. No./Substance:
0/Interferon-alpha

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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