| A case of a choledochal cyst associated with a lymphatic infiltration of a hyperplastic gallbladder epithelium. | |
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MedLine Citation:
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PMID: 19361649 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 4-year-old girl with a congenital choledochal cyst (Todani IV-A, Komi type A) underwent a resection of the dilated common bile duct and gallbladder. Histologic studies of the gallbladder showed a general hyperplastic change associated with cribriform proliferation at the gland base of the gallbladder. In this region, clusters of cribriform glands were found within the lymphatic vessels, compatible with lymphatic infiltration of tumor cells. However, careful histologic studies did not reveal any apparent neoplastic changes in the gallbladder and common bile duct, so a final diagnosis of epithelial atypism with reactive hypertrophy was made. The displacements observed in the lymphatics are just an incidental finding in a proliferative process of the hyperplastic gallbladder epithelium. In the follow-up observation for 3 years, the patient is doing well without evidence of tumor recurrence. These results suggest that a mere lymphatic infiltration of hyperplastic gallbladder epithelium should not be directly considered as evidence of carcinogenesis. |
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Authors:
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Yutaka Hirayama; Masayuki Kubota; Go Hasegawa; Naoki Okuyama; Masahiro Ohtaki; Kumiko Kobayashi; Mami Tsukada; Kanako Sato; Ken Nishikura; Makoto Naito; Yoichi Ajioka |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of pediatric surgery Volume: 44 ISSN: 1531-5037 ISO Abbreviation: J. Pediatr. Surg. Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-04-13 Completed Date: 2009-08-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0052631 Medline TA: J Pediatr Surg Country: United States |
Other Details:
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Languages: eng Pagination: 831-5 Citation Subset: IM |
Affiliation:
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Department of Pediatric Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan. you4141@aol.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Child, Preschool Cholecystectomy / methods Choledochal Cyst / diagnosis*, surgery Common Bile Duct / pathology*, surgery Diagnosis, Differential Epithelium / pathology Female Follow-Up Studies Gallbladder / pathology*, surgery Gallbladder Neoplasms / diagnosis*, pathology Humans Hyperplasia / pathology Immunohistochemistry Incidental Findings Lymphatic Vessels / pathology*, physiopathology Risk Assessment Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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