| A case of bleomycin-induced acral erythema (AE) with eccrine squamous syringometaplasia (ESS) and summary of reports of AE with ESS in the literature. | |
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MedLine Citation:
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PMID: 16361756 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Chemotherapy-induced acral erythema (AE) is primarily induced by hydroxyurea, methotrexate, and cytarabine, although there are rare reports of AE induced by combination chemotherapy containing bleomycin. It is thought that the accumulation of chemotherapeutic drugs in eccrine glands may cause eccrine squamous syringometaplasia (ESS), which is characterized by metaplasia and focal necrosis of the epithelium of the eccrine duct. ESS is occasionally detected in conjunction with AE, but such occurrences are relatively uncommon. This is the first report of AE with ESS induced by the administration of bleomycin alone. We also provide a summary of past cases of AE with ESS in the literature. |
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Authors:
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Hiromi Tsuboi; Kohzoh Yonemoto; Kensei Katsuoka |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: The Journal of dermatology Volume: 32 ISSN: 0385-2407 ISO Abbreviation: J. Dermatol. Publication Date: 2005 Nov |
Date Detail:
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Created Date: 2005-12-19 Completed Date: 2006-01-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7600545 Medline TA: J Dermatol Country: Japan |
Other Details:
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Languages: eng Pagination: 921-5 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Kitasato University School of Medicine, Kanagawa, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antimetabolites, Antineoplastic
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adverse effects* Bleomycin / adverse effects* Eccrine Glands / pathology* Erythema / chemically induced* Humans Male Metaplasia / chemically induced Middle Aged Necrosis / chemically induced |
| Chemical | |
Reg. No./Substance:
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0/Antimetabolites, Antineoplastic; 11056-06-7/Bleomycin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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