| A case of autoimmune progesterone dermatitis diagnosed by progesterone pessary. | |
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MedLine Citation:
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PMID: 21605100 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Autoimmune progesterone dermatitis is a rare, cyclical eruption that occurs in the luteal phase of the menstrual cycle and during pregnancy. Many manifestations have been reported including cyclical eczema, urticaria, erythema multiforme, stomatitis and even anaphylaxis. The condition spontaneously resolves after menopause. As histopathology is non-specific, the diagnosis rests on history with precipitation of the eruption by a progesterone challenge, usually by the intradermal, intramuscular or oral route. We present the case of a 34-year-old woman with a premenstrual papular and eczematous eruption that was exacerbated after pregnancy. Biopsy showed subacute spongiotic dermatitis. To confirm the diagnosis, we used an intravaginal progesterone pessary as a provocation challenge. There was recurrence of the rash 12 h after insertion of the pessary with spontaneous resolution thereafter. We propose that use of a progesterone pessary is an effective tool in the diagnosis of autoimmune progesterone dermatitis. |
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Authors:
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Katie Le; Glenda Wood |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Australasian journal of dermatology Volume: 52 ISSN: 1440-0960 ISO Abbreviation: Australas. J. Dermatol. Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-05-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0135232 Medline TA: Australas J Dermatol Country: Australia |
Other Details:
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Languages: eng Pagination: 139-41 Citation Subset: IM |
Copyright Information:
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© 2011 The Authors. Australasian Journal of Dermatology © 2011 The Australasian College of Dermatologists. |
Affiliation:
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Skin and Cancer Foundation Department of Dermatology, Prince of Wales Hospital, Sydney, New South Wales, Australia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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