Document Detail


A case of apical ballooning syndrome in a male with status asthmaticus; highlighting the role of B2 agonists in the pathophysiology of a reversible cardiomyopathy.
MedLine Citation:
PMID:  23882408     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Apical ballooning syndrome (ABS), also known as Takotsubo cardiomyopathy, was first reported by Dote and colleagues in Japanese literature in 1991 in a review of five cases. Case series have highlighted the association of severe psychological stressors as the major precipitating factors of this syndrome. Status Epilepticus and Sub-Arachnoid hemorrhage are also now established independent etiologies for this phenomenon in patients without coronary artery disease. We report a case of reversible apical ventricular dysfunction in a 50-year-old male presenting with status asthmaticus who quickly underwent intubation. Following this, he had ST elevations in precordial leads with mild cardiac enzyme leak. Subsequent cardiac catheterization revealed a left ventricular ejection fraction of 25-30% with apical aneurismal segment. No obstructive disease was observed. Three days later there was marked clinical improvement; the patient was extubated and repeat echocardiography revealed a remarkable return to normal ventricular size and systolic function. Our case demonstrates that excess use of beta-agonists may be a potential risk factor for ABS and raises the possibility of cathecholamine cardiotoxicity being mediated via beta-receptors. Furthermore, it also negates the propensity of apical ballooning so far reported only in women with respiratory distress without confounding emotional stressors.
Authors:
Farah F Salahuddin; Peter Sloane; Philip Buescher; Lev Agarunov; Divya Sreeramoju
Related Documents :
23430858 - Primary carnitine deficiency presents atypically with long qt syndrome: a case report.
16173418 - Leprosy elimination campaigns in orissa.
17995538 - Relapsing vivax malaria after 6 months of daily atovaquone/proguanil in afghanistan: th...
9373558 - Tuberculoma of the cheek: a case report.
3535628 - Orthodontic/orthopaedic adjunct of fixed orthodontic appliances.
23107638 - Mycobacterium africanum, an emerging disease in high-income countries?
Publication Detail:
Type:  Journal Article     Date:  2013-07-05
Journal Detail:
Title:  Journal of community hospital internal medicine perspectives     Volume:  3     ISSN:  2000-9666     ISO Abbreviation:  J Community Hosp Intern Med Perspect     Publication Date:  2013  
Date Detail:
Created Date:  2013-07-24     Completed Date:  2013-07-24     Revised Date:  2013-07-26    
Medline Journal Info:
Nlm Unique ID:  101601396     Medline TA:  J Community Hosp Intern Med Perspect     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Medicine, Medstar Union Memorial Hospital, Baltimore, MD, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Pylephlebitis: a rare complication of an intra-abdominal infection.
Next Document:  Stage-specific epigenetic gene silencing during thymocyte lineage commitment.