Document Detail

A case of antiphospholipid syndrome with cutaneous ulcer and intrauterine fetal growth retardation.
MedLine Citation:
PMID:  12928543     Owner:  NLM     Status:  MEDLINE    
A 28-year-old patient presented with severe intrauterine fetal growth retardation (IUGR) at 34 weeks' gestation. There was a prior history of a recurrent cutaneous ulcer on the left thigh. Serological tests for IgG anticardiolipin antibody were positive. A live premature male infant was delivered by an urgent cesarean section because of fetal distress. Histopathological examination revealed that the causes of the cutaneous ulcer and IUGR were thrombosis of the small blood vessels and placental infarction, respectively. Early diagnosis and proper treatment are important in the management of the antiphospholipid syndrome.
Junji Nakano; Mitsutaka Nakamura; Takehisa Ito; Masako Murata; Jun-Ichi Fujiyama
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of dermatology     Volume:  30     ISSN:  0385-2407     ISO Abbreviation:  J. Dermatol.     Publication Date:  2003 Jul 
Date Detail:
Created Date:  2003-08-20     Completed Date:  2003-09-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7600545     Medline TA:  J Dermatol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  533-7     Citation Subset:  IM    
Department of Dermatology, Tokuyama Central Hospital, Tokuyama, Japan.
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MeSH Terms
Antiphospholipid Syndrome / complications,  pathology*
Biopsy, Needle
Cesarean Section
Fetal Growth Retardation / complications,  pathology*
Follow-Up Studies
Gestational Age
Pregnancy Complications / diagnosis*
Pregnancy Outcome*
Risk Assessment
Skin Ulcer / complications,  pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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