| A case of Takayasu's arteritis and aortic regurgitation, which presented much difficulty in the diagnosing process because of complicated osteomyelitis and non-typical manifestations. | |
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MedLine Citation:
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PMID: 19632536 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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A 49-year-old woman presenting with leg edema and progressive dyspnea on exertion was found to have a diastolic murmur. Echocardiography revealed increased left ventricular volume and severe aortic regurgitation (AR). She also had pain in her chest and left shoulder. Gallium scintigraphy showed increased uptake in the sternum, and further examination indicated chronic osteomyelitis in the sternum and the proximal portion of bilateral clavicles. Aortic valve replacement was performed and the ascending aorta was found to have inflammatory wall thickening with adhesion formation. Histological study and other postoperative examinations revealed Takayasu's arteritis (TA). Involvement of bone is rarely described in TA, and typical manifestations such as claudication of extremities, decreased brachial artery pulse, and arteriogram abnormality were absent, which made the preoperative diagnosis difficult. Here we report a case of severe AR due to TA which presented much difficulty in the diagnosing process, because a rare complicated illness, osteomyelitis was clinically apparent and there were few clinical manifestations related to TA. |
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Authors:
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Atsushi Hoshino; Takahisa Sawada; Megumi Matsuda; Sonoko Miyagawa; Takeshi Nakamura; Hiroaki Matsubara |
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Publication Detail:
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Type: Journal Article Date: 2008-12-16 |
Journal Detail:
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Title: Journal of cardiology Volume: 54 ISSN: 1876-4738 ISO Abbreviation: J Cardiol Publication Date: 2009 Aug |
Date Detail:
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Created Date: 2009-07-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8804703 Medline TA: J Cardiol Country: Japan |
Other Details:
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Languages: eng Pagination: 148-52 Citation Subset: IM |
Affiliation:
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Kyoto Prefectural University of Medicine, Department of Cardiology, Kyoto, Japan. a-hoshi@koto.kpu-m.ac.jp |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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