Document Detail

A case of Peutz-Jeghers syndrome with nasal polyposis, extreme iron deficiency anemia, and hamartoma-adenoma transformation: management by combined surgical and endoscopic approach.
MedLine Citation:
PMID:  7639241     Owner:  NLM     Status:  MEDLINE    
We report a rare variant of Peutz-Jeghers syndrome identified by the presence of nasal polyposis and extreme anemia. Multiple hamartomatous polyps were found throughout the upper and lower gastrointestinal tract. We conducted a combined surgical-endoscopic approach to prevent the development of a short-bowel syndrome. The polyps removed by snare and surgical polypectomy showed features typical of harmartomas. Three colonic polyps and two nasal polyps showed histological evidence of adenomatous change. This adenomatous change seems to fit into the pathogenic sequence of hamartoma-adenoma.
L De Facq; J De Sutter; M De Man; P Van der Spek; L Lepoutre
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  90     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  1995 Aug 
Date Detail:
Created Date:  1995-09-08     Completed Date:  1995-09-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1330-2     Citation Subset:  IM    
Department of Gastroenterology, Onze Lieve Vrouw Hospital, Aalst, Belgium.
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MeSH Terms
Anemia, Iron-Deficiency / etiology*
Colon / pathology
Combined Modality Therapy
Duodenum / pathology
Endoscopy, Gastrointestinal
Jejunum / pathology
Nasal Polyps / complications*
Peutz-Jeghers Syndrome / complications*,  pathology,  therapy*
Comment In:
Am J Gastroenterol. 1996 Oct;91(10):2252-3   [PMID:  8855772 ]

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