Document Detail

A case of Leigh's disease with initial manifestation of dystonia.
MedLine Citation:
PMID:  2281687     Owner:  NLM     Status:  MEDLINE    
A case of Leigh's disease (subacute necrotizing encephalomyelopathy) is reported with such noteworthy features as early onset, dystonia, paraparesis the presence of low attenuation areas in both basal ganglias on computerized tomography of the brain and the presence of a high signal intensity in both basal ganglias in T2 weighted image by MR. The electron microscopic findings of muscle biopsy are suggestive of pleoconial mitochondrial myopathy.
C W Chung; S H Hwang; Y C Choi; Y H Sohn; J S Kim; B C Lee; J G Chi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Yonsei medical journal     Volume:  31     ISSN:  0513-5796     ISO Abbreviation:  Yonsei Med. J.     Publication Date:  1990 Sep 
Date Detail:
Created Date:  1991-03-14     Completed Date:  1991-03-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0414003     Medline TA:  Yonsei Med J     Country:  KOREA    
Other Details:
Languages:  eng     Pagination:  274-9     Citation Subset:  IM    
Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.
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MeSH Terms
Basal Ganglia / pathology
Dystonia / diagnosis,  etiology*
Energy Metabolism
Leigh Disease / diagnosis*,  metabolism,  pathology
Muscles / pathology

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