Document Detail

A case of Fisher syndrome with multiple cranial neuropathy and abnormal EEG findings.
MedLine Citation:
PMID:  23268979     Owner:  NLM     Status:  In-Data-Review    
A 69-year-old woman was admitted because of unconsciousness and multiple cranial neuropathy. She had suffered diarrhea 2 weeks previously. On examination, she was noted to have total external and internal ophthalmoplegia, bilateral facial palsy, dysphagia, dysarthria, neck weakness, distal motor weakness of all limbs, and ataxia. She had also presented with hyporeflexia and hypoesthesia, but with a bilateral pyramidal tract sign. A study of her cerebrospinal fluid revealed albuminocytologic dissociation, and nerve conduction study revealed demyelination of her peripheral nerves. Moreover, electroencephalography findings were abnormal and anti-GQ1b antibody was positive. We diagnosed Fisher syndrome with Guillain-Barré syndrome and Bickerstaff brainstem encephalitis. We administered intravenous immunoglobulin treatment for 5 days and her symptoms gradually improved. However, her external ophthalmoplegia continued for several months.
Masayuki Ochi; Nako Shinohara; Kenji Kamogawa; Yoko Okada; Tokihisa Nagai; Keiko Taguchi; Rie Takita; Michiya Igase; Katsuhiko Kohara; Tetsuro Miki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics     Volume:  49     ISSN:  0300-9173     ISO Abbreviation:  Nihon Ronen Igakkai Zasshi     Publication Date:  2012  
Date Detail:
Created Date:  2012-12-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7507332     Medline TA:  Nihon Ronen Igakkai Zasshi     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  367-71     Citation Subset:  IM    
Department of Geriatric Medicine, Medicine and Bioscience, Graduate School of Medicine, Ehime University.
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