Document Detail

A case of Collet-Sicard syndrome presenting to the Oral and Maxillofacial Surgery Department and a review of the literature.
MedLine Citation:
PMID:  20018414     Owner:  NLM     Status:  MEDLINE    
A case of Collet-Sicard Syndrome caused by skull base metastasis of probable breast adenocarcinoma is reported. A 79-year-old lady presented to the Oral and Maxillofacial Surgery Department with progressive left-sided tongue symptoms that she described as swelling. This was initially attributed to local disease, and a biopsy showed the patient was suffering from Necrotizing Sialometaplasia. However, her symptoms rapidly evolved into cranial nerve palsies affecting IX-XII, not initially diagnosed. Subsequent imaging revealed the cause of her worsening symptoms to be a metastatic lesion at her left skull base. Cranial nerve palsies due to metastases to the skull base are rare, and the authors would advise clinicians to adopt a high-index of suspicion in ruling out cranial nerve pathology at the skull base when encountering unusual signs and symptoms in the head and neck region.
Neil John Opie; Khaleeq Ur-Rehman; Graham J James
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2009-12-16
Journal Detail:
Title:  The British journal of oral & maxillofacial surgery     Volume:  48     ISSN:  1532-1940     ISO Abbreviation:  Br J Oral Maxillofac Surg     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-17     Completed Date:  2010-08-18     Revised Date:  2010-09-28    
Medline Journal Info:
Nlm Unique ID:  8405235     Medline TA:  Br J Oral Maxillofac Surg     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  e9-11     Citation Subset:  D; IM    
Copyright Information:
Copyright 2009 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
Worcestershire Royal Hospital, Charles Hastings Way, Worcester, WR5 1DD, UK.
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MeSH Terms
Accessory Nerve Diseases / etiology
Adenocarcinoma / secondary*
Breast Neoplasms / pathology
Cranial Nerve Diseases / etiology*
Diagnosis, Differential
Glossopharyngeal Nerve Diseases / etiology
Hypoglossal Nerve Diseases / etiology
Paralysis / etiology*
Sialometaplasia, Necrotizing / diagnosis
Skull Base Neoplasms / secondary*
Tongue Diseases / diagnosis
Vagus Nerve Diseases / etiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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