Document Detail

A case of Aspergillus myocarditis associated with septic shock.
MedLine Citation:
PMID:  9892537     Owner:  NLM     Status:  MEDLINE    
We report a case of isolated myocardial involvement due to Aspergillus sp., in a patient with multiple organ failure but no demonstrable immune deficiency apart from corticosteroid therapy given for the three weeks prior to hospitalization. This patient died of septic shock 7 days after hospitalization. Aspergillus was isolated only once from a sputum specimen obtained 24 h before death. At post-mortem examination there are emboli and myocardial lesions containing clusters of hyphae as Aspergillus confirmed by indirect immunofluorescence. The other organs were free of fungi. This observation is remarkable because the cardiac involvement was isolated and no immunodeficiency was present.
Y Rouby; E Combourieu; J D Perrier-Gros-Claude; C Saccharin; M Huerre
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of infection     Volume:  37     ISSN:  0163-4453     ISO Abbreviation:  J. Infect.     Publication Date:  1998 Nov 
Date Detail:
Created Date:  1999-03-10     Completed Date:  1999-03-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7908424     Medline TA:  J Infect     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  295-7     Citation Subset:  IM    
Microbiology Laboratory, Desgenettes Military Hospital, Lyon, France.
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MeSH Terms
Aspergillosis / complications*
Aspergillus / isolation & purification
Fatal Outcome
Myocarditis / etiology*,  microbiology,  pathology
Shock, Septic / complications*

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