| Is carnitine essential in children? | |
| | |
MedLine Citation:
|
PMID: 1864456 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Carnitine has a fundamental biological role as a long-chain fatty acid carrier across the mitochondrial membrane and in ketone body formation. Although the body normally synthesizes carnitine, in certain circumstances such as total parenteral nutrition and haemodialysis a dietary supplement may be needed to maintain adequate levels. Several considerations suggest that carnitine is a truly essential nutrient in infancy and in other situations where the energy requirement is particularly high, e.g. pregnancy and breast feeding. There are, for example, congenital deficit syndromes due to enzymatic inadequacies. There is also the possible role of carnitine in serious metabolic disorders such as organic acidaemias and, above all, it has multiple physiological functions in major metabolic pathways which are essential for development and growth. |
| | |
Authors:
|
M Giovannini; C Agostoni; P C Salari |
Related Documents
:
|
22061326 - Fatty acid profile, cholesterol content and tenderness of meat from podolian young bulls. 1401366 - Interactions between gluconeogenesis and fatty acid oxidation in isolated sheep hepatoc... 2438746 - Disorders related to the metabolism of phytanic acid. 8034586 - Arachidonic acid formed by peroxisomal beta-oxidation of 7,10,13,16-docosatetraenoic ac... 3112486 - Medium chain triglycerides and structured lipids. 591256 - Recirculation of iopanoic acid after conjugation in the liver. |
Publication Detail:
|
Type: Comparative Study; Journal Article; Review |
Journal Detail:
|
Title: The Journal of international medical research Volume: 19 ISSN: 0300-0605 ISO Abbreviation: J. Int. Med. Res. Publication Date: 1991 Mar-Apr |
Date Detail:
|
Created Date: 1991-09-11 Completed Date: 1991-09-11 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0346411 Medline TA: J Int Med Res Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 88-102 Citation Subset: IM |
Affiliation:
|
Fifth Department of Paediatrics, University of Milan, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Carnitine / deficiency, metabolism*, therapeutic use Female Humans Infant Infant, Newborn Kidney / metabolism Liver / metabolism Metabolism, Inborn Errors / physiopathology Milk, Human / chemistry Nutritional Requirements Pregnancy Rats |
| Chemical | |
Reg. No./Substance:
|
541-15-1/Carnitine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Clinical and pharmacological review of the efficacy of orphenadrine and its combination with paracet...
Next Document: Neurons are replenished in cultures of embryonic chick optic tectum after immunomagnetic depletion.