Document Detail

The cardiovascular helix: a three-dimensional view of blood pressure and heart rate over time.
MedLine Citation:
PMID:  10234119     Owner:  NLM     Status:  Publisher    
BACKGROUND: The baroreflex system plays an important role in the fast regulation of blood pressure. Conventional determination of baroreflex sensitivity either by pharmacological or by physical methods has proven cumbersome. Alternative approaches are based on continuously recording data of systolic arterial blood pressure (SAP) and heart rate, with evaluation by regression assessment or spectral analysis. Data selection for both methods results in various conflicts. We therefore developed a non-invasive method to evaluate baroreceptor functioning on the basis of a visual representation that would be independent of the restrictions related to regression and spectral analysis.METHODS: By plotting SAP and heart rate (measured by using a Finapres device) of 33 young men against time in a three-dimensional space, a helical structure could be visualized for subjects at rest as well as under stress. The shape of the helix was determined by the phase lag between SAP and heart rate and by the amplitude ratio. On the basis of this helix a model using two sinusoidal representations of SAP and heart rate parameterized the interaction between blood pressure and heart rate. The transfer function analysis was studied by means of a curve-fitting method similar to the Monte Carlo method. RESULTS: We found baroreceptor gain mode to be 9 ms/mmHg for subjects under stress and 11 ms/mmHg for subjects at rest. The values of phase lag between SAP and heart rate tended to gather around approximately 90 degrees. CONCLUSION: This method can be applied using even small sets of data over random periods of time.
Kollenbaum; Schnoor; Meyer; Meyer
Related Documents :
943469 - Heart rate and avoidance conditioned activity in rats.
24100169 - Neonatal hypotension: dopamine or dobutamine?
2100349 - Cardiopulmonary adjustments during operant heart rate control.
3881499 - Plasma epinephrine concentration in healthy men: correlation with systolic pressure and...
24317019 - Pulmonary arterial systolic pressure and e/e' in the evaluation of left ventricular fil...
6742149 - Assessment of parasympathetic control of heart rate by a noninvasive method.
21931129 - Intraocular pressure and corneal biomechanics in an adult british population: the epic-...
2237179 - Future perspectives: diagnostic possibilities with positron emission tomography.
2898209 - Cardiovascular pharmacology of dopexamine in low output congestive heart failure.
Publication Detail:
Journal Detail:
Title:  Blood pressure monitoring     Volume:  2     ISSN:  1473-5725     ISO Abbreviation:  Blood Press Monit     Publication Date:  1997 Oct 
Date Detail:
Created Date:  1999-05-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606438     Medline TA:  Blood Press Monit     Country:  -    
Other Details:
Languages:  ENG     Pagination:  207-215     Citation Subset:  -    
Clinic of Nephrology, I. Medizinische Universitätsklinik, Kiel, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Hypertension management in managed care: the role of home blood pressure monitoring.
Next Document:  Clinical use of ambulatory blood pressure monitoring in a Veteran's Medical Center.