Document Detail


The cardiovascular effects of flaxseed and its omega-3 fatty acid, alpha-linolenic acid.
MedLine Citation:
PMID:  21076723     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Preventing the occurrence of cardiovascular disease (CVD) with nutritional interventions is a therapeutic strategy that may warrant greater research attention. The increased use of omega (ω)-3 fatty acids is a powerful example of one such nutritional strategy that may produce significant cardiovascular benefits. Marine food products have provided the traditional dietary sources of ω-3 fatty acids. Flaxseed is an alternative to marine products. It is one of the richest sources of the plant-based ω-3 fatty acid, alpha-linolenic acid (ALA). Based on the results of clinical trials, epidemiological investigations and experimental studies, ingestion of ALA has been suggested to have a positive impact on CVD. Because of its high ALA content, the use of flaxseed has been advocated to combat CVD. The purpose of the present review was to identify the known cardiovascular effects of flaxseed and ALA and, just as importantly, what is presently unknown.
Authors:
Delfin Rodriguez-Leyva; Chantal M C Dupasquier; Richelle McCullough; Grant N Pierce
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  The Canadian journal of cardiology     Volume:  26     ISSN:  1916-7075     ISO Abbreviation:  Can J Cardiol     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-15     Completed Date:  2010-12-31     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  8510280     Medline TA:  Can J Cardiol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  489-96     Citation Subset:  IM    
Affiliation:
Institute of Cardiovascular Sciences, St Boniface Hospital Research Centre and Department of Physiology, University of Manitoba, Winnipeg, Manitoba.
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MeSH Terms
Descriptor/Qualifier:
Cardiovascular Diseases / prevention & control*
Clinical Trials as Topic
Evidence-Based Medicine
Flax*
Humans
Phytotherapy*
Seeds*
Treatment Outcome
alpha-Linolenic Acid / administration & dosage,  therapeutic use*
Grant Support
ID/Acronym/Agency:
//Canadian Institutes of Health Research
Chemical
Reg. No./Substance:
463-40-1/alpha-Linolenic Acid
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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