Document Detail

The cardiorespiratory effects of ICI 35 868 in patients with valvular heart disease.
MedLine Citation:
PMID:  6334454     Owner:  NLM     Status:  MEDLINE    
The haemodynamic effects at induction of anaesthesia with ICI 35 868 (1.5 mg/kg) are reported in ten patients with severe aortic or mitral valve disease. The average decrease of mean arterial pressure was 19.1% (p less than 0.01), heart rate decreased by 10% (p less than 0.01). Cardiac index and stroke volume index were both little changed but there were significant reductions in rate pressure product and left ventricular stroke work index (p less than 0.01).
C Aun; E Major
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anaesthesia     Volume:  39     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:  1984 Nov 
Date Detail:
Created Date:  1984-12-27     Completed Date:  1984-12-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1096-100     Citation Subset:  AIM; IM    
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MeSH Terms
Anesthesia, Intravenous*
Anesthetics / pharmacology*
Aortic Valve / surgery
Heart Valve Diseases / physiopathology*,  surgery
Heart Valve Prosthesis
Hemodynamics / drug effects*
Middle Aged
Mitral Valve / surgery
Phenols / pharmacology*
Respiration / drug effects*
Time Factors
Reg. No./Substance:
0/Anesthetics; 0/Phenols; 2078-54-8/Propofol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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