| The cardiorespiratory control hypothesis for sudden infant death syndrome. | |
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MedLine Citation:
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PMID: 1464189 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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One or more abnormalities in cardiorespiratory control is the most compelling explanation for SIDS. Elucidation of the interrelationships between arousal responsiveness and gasping may be crucial to a better understanding of SIDS pathophysiology. The complex interactions need to be examined between arousal, autoresuscitation, and the other components of cardiorespiratory control. Prospective identification trials will be difficult since no cardiorespiratory control parameter yet identified has sufficient sensitivity and specificity, and trials assessing multiple parameters will be costly and cumbersome. Furthermore, prospective identification will be worthwhile only if an effective intervention has been established. To the extent that SIDS deaths still occur during documented monitoring, detailed analyses of the recorded cardiorespiratory events should finally provide us with objective data as to the terminal pathophysiologic events in SIDS victims and their relationship to aberrant cardiorespiratory control. |
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Authors:
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C E Hunt |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Clinics in perinatology Volume: 19 ISSN: 0095-5108 ISO Abbreviation: Clin Perinatol Publication Date: 1992 Dec |
Date Detail:
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Created Date: 1993-01-21 Completed Date: 1993-01-21 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 7501306 Medline TA: Clin Perinatol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 757-71 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Medical College of Ohio, Toledo. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Arousal Arrhythmias, Cardiac / complications* Body Temperature Regulation Brain Stem / physiopathology Chemoreceptor Cells / physiology Heart / innervation, physiopathology Humans Infant Respiration / physiology Respiration Disorders / complications* Respiratory System / innervation Sudden Infant Death / etiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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