| The cardiac cycle and the physiologic basis of left ventricular contraction, ejection, relaxation, and filling. | |
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MedLine Citation:
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PMID: 18313620 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Heart failure is defined as the pathologic state in which the heart is unable to pump blood at a rate required by the metabolizing tissues or can do so only with an elevated filling pressure. Heart failure in adults most frequently results from the inability of the left ventricle to fill (diastolic performance) or eject (systolic performance) blood. The severity of heart failure and its prognosis are more closely related to the degree of diastolic filling abnormalities than the ejection fraction, which underscores the importance of understanding the mechanisms of diastolic abnormalities in heart failure. |
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Authors:
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Hidekatsu Fukuta; William C Little |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Heart failure clinics Volume: 4 ISSN: 1551-7136 ISO Abbreviation: Heart Fail Clin Publication Date: 2008 Jan |
Date Detail:
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Created Date: 2008-03-03 Completed Date: 2008-03-25 Revised Date: 2010-12-17 |
Medline Journal Info:
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Nlm Unique ID: 101231934 Medline TA: Heart Fail Clin Country: United States |
Other Details:
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Languages: eng Pagination: 1-11 Citation Subset: IM |
Affiliation:
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Nagoya City University, Nagoya, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Diastole Exercise Tolerance Heart Failure / physiopathology* Humans Myocardial Contraction Myocardium* Stroke Volume / physiology* Systole Ventricular Function* |
| Grant Support | |
ID/Acronym/Agency:
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R01 AA012335-05/AA/NIAAA NIH HHS; R01 HL053541-04/HL/NHLBI NIH HHS; R01 HL074318-04/HL/NHLBI NIH HHS; R29 HL045258-05/HL/NHLBI NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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