Document Detail


The cardiac actin locus (Actc-1) is not on mouse chromosome 17 but is linked to beta 2-microglobulin on chromosome 2.
MedLine Citation:
PMID:  2570027     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A restriction fragment variant and recombinant inbred strains were used to show that the cardiac actin locus (Actc-1) is closely linked to beta 2-microglobulin (B2m) and several other loci on chromosome 2 of the mouse. Close linkage of Actc-1 and B2m in both man and mouse provides another example of a chromosomal segment that has been conserved since the divergence of the lineages leading to these two species.
Authors:
J L Crosby; S J Phillips; J H Nadeau
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Genomics     Volume:  5     ISSN:  0888-7543     ISO Abbreviation:  Genomics     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1989-09-29     Completed Date:  1989-09-29     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8800135     Medline TA:  Genomics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  19-23     Citation Subset:  IM    
Affiliation:
Jackson Laboratory, Bar Harbor, Maine 04609.
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MeSH Terms
Descriptor/Qualifier:
Alleles
Animals
Chromosome Mapping*
Chromosomes, Human, Pair 15
Humans
Linkage (Genetics)*
Mice
Mice, Inbred Strains
Polymorphism, Restriction Fragment Length
Species Specificity
beta 2-Microglobulin / genetics*
Grant Support
ID/Acronym/Agency:
GM32461/GM/NIGMS NIH HHS; GM39414/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/beta 2-Microglobulin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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