Document Detail

Is carbamazepine safe to take during pregnancy?
MedLine Citation:
PMID:  22337738     Owner:  NLM     Status:  MEDLINE    
QUESTION: Some of my pregnant patients are afraid to take their antiepileptic drugs during pregnancy because of the known risk of malformations and the neurodevelopmental problems associated with valproic acid. Are there similar concerns with carbamazepine?
ANSWER: Similar to valproic acid, carbamazepine increases the risk of neural tube defects; however, it does not increase the risk of other malformations. Carbamazepine is also not associated with an increased risk of developmental delay.
Jeremy Matlow; Gideon Koren
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian family physician Médecin de famille canadien     Volume:  58     ISSN:  1715-5258     ISO Abbreviation:  Can Fam Physician     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-02-16     Completed Date:  2012-09-20     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  0120300     Medline TA:  Can Fam Physician     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  163-4     Citation Subset:  IM    
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MeSH Terms
Abnormalities, Drug-Induced
Anticonvulsants / adverse effects*
Carbamazepine / adverse effects*
Epilepsy / drug therapy*
Neural Tube Defects / chemically induced*
Pregnancy Complications / drug therapy*
Reg. No./Substance:
0/Anticonvulsants; 298-46-4/Carbamazepine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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