| The canine and feline skin microbiome in health and disease. | |
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MedLine Citation:
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PMID: 23331690 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The skin harbours a diverse and abundant, yet inadequately investigated, microbial population. The population is believed to play an important role in both the pathophysiology and the prevention of disease, through a variety of poorly explored mechanisms. Early studies of the skin microbiota in dogs and cats reported a minimally diverse microbial composition of low overall abundance, most probably as a reflection of the limitations of testing methodology. Despite these limitations, it was clear that the bacterial population of the skin plays an important role in disease and in changes in response to both infectious and noninfectious diseases. Recent advances in technology are challenging some previous assumptions about the canine and feline skin microbiota and, with preliminary application of next-generation sequenced-based methods, it is apparent that the diversity and complexity of the canine skin microbiome has been greatly underestimated. A better understanding of this complex microbial population is critical for elucidation of the pathophysiology of various dermatological (and perhaps systemic) diseases and to develop novel ways to manipulate this microbial population to prevent or treat disease. |
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Authors:
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J Scott Weese |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Veterinary dermatology Volume: 24 ISSN: 1365-3164 ISO Abbreviation: Vet. Dermatol. Publication Date: 2013 Feb |
Date Detail:
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Created Date: 2013-01-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9426187 Medline TA: Vet Dermatol Country: England |
Other Details:
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Languages: eng Pagination: 137-e31 Citation Subset: IM |
Copyright Information:
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© 2013 The Author. Veterinary Dermatology © 2013 ESVD and ACVD. |
Affiliation:
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Department of Pathobiology, Centre for Public Health and Zoonoses, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada N1G 2W1. |
Export Citation:
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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