Document Detail


cDNA cloning and sequencing of rat monoamine oxidase A: comparison with the human and bovine enzymes.
MedLine Citation:
PMID:  1526120     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. The nucleotide and deduced amino acid sequences of rat liver MAO A were determined, and sequence identities among MAO A and B from rat, human and bovine were compared. 2. MAO A from rat exhibited greater than 85% sequence identity with bovine and human MAO A, and 70% identity with rat MAO B. 3. Rat adrenal cDNAs were restriction mapped, partially sequenced and found to be identical to rat liver MAO A, suggesting that these two tissues express the same polypeptide.
Authors:
S W Kwan; C W Abell
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Comparative biochemistry and physiology. B, Comparative biochemistry     Volume:  102     ISSN:  0305-0491     ISO Abbreviation:  Comp. Biochem. Physiol., B     Publication Date:  1992 May 
Date Detail:
Created Date:  1992-10-22     Completed Date:  1992-10-22     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  2984730R     Medline TA:  Comp Biochem Physiol B     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  143-7     Citation Subset:  IM    
Affiliation:
Division of Medicinal Chemistry, College of Pharmacy, University of Texas, Austin 78712.
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MeSH Terms
Descriptor/Qualifier:
Adrenal Medulla / enzymology
Amino Acid Sequence
Animals
Base Sequence
Cattle
Cloning, Molecular
DNA / genetics*
Humans
Liver / enzymology
Molecular Sequence Data
Monoamine Oxidase / genetics*
Rats
Restriction Mapping
Sequence Homology, Nucleic Acid
Species Specificity
Grant Support
ID/Acronym/Agency:
NS 24932/NS/NINDS NIH HHS
Chemical
Reg. No./Substance:
9007-49-2/DNA; EC 1.4.3.4/Monoamine Oxidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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