Document Detail


cAMP levels in fast- and slow-twitch skeletal muscle after an acute bout of aerobic exercise.
MedLine Citation:
PMID:  8392799     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The present study examined whether exercise duration was associated with elevated and/or sustained elevations of postexercise adenosine 3',5'-cyclic monophosphate (cAMP) by measuring cAMP levels in skeletal muscle for up to 4 h after acute exercise bouts of durations that are known to either produce (60 min) or not produce (10 min) mitochondrial proliferation after chronic training. Treadmill-acclimatized, but untrained, rats were run at 22 m/min for 0 (control), 10, or 60 min and were killed at various postexercise (0, 0.5, 1, 2, and 4 h) time points. Fast-twitch white and red (quadriceps) and slow-twitch (soleus) muscles were quickly excised, frozen in liquid nitrogen, and assayed for cAMP with a commercial kit. Unexpectedly, cAMP contents in all three muscles were similar to control (nonexercise) at most (21 of 30) time points after a single 10- or 60-min run. Values at 9 of 30 time points were significantly different from control (P < 0.05); i.e., 3 time points were significantly higher than control and 6 were significantly less than control. These data suggest that the cAMP concentration of untrained skeletal muscle after a single bout of endurance-type exercise is not, by itself, associated with exercise duration.
Authors:
A Sheldon; F W Booth; C R Kirby
Related Documents :
20839489 - Is there a role for micrornas in exercise immunology? a synopsis of current literature ...
12563009 - Exercise induces transient transcriptional activation of the pgc-1alpha gene in human s...
2927299 - Naloxone does not affect muscle blood flow during low intensity exercise in rats.
20224659 - The role of exercise-induced myokines in muscle homeostasis and the defense against chr...
2297859 - Skeletal muscle biochemistry and histology in ambulatory patients with long-term heart ...
9950919 - Effect of endurance exercise on myosin heavy chain gene regulation in human skeletal mu...
15596479 - Seasonal change in the balance between capacities of rubp carboxylation and rubp regene...
9562159 - Perception of pain after resistance exercise.
23140359 - Breathing training characterization by thermal imaging: a case study.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of physiology     Volume:  264     ISSN:  0002-9513     ISO Abbreviation:  Am. J. Physiol.     Publication Date:  1993 Jun 
Date Detail:
Created Date:  1993-08-13     Completed Date:  1993-08-13     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370511     Medline TA:  Am J Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  C1500-4     Citation Subset:  IM; S    
Affiliation:
Department of Physiology and Cell Biology, University of Texas Medical School, Houston 77225.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Cyclic AMP / metabolism*
Ethanol
Isoproterenol / pharmacology
Male
Methods
Muscle Contraction*
Muscles / metabolism*
Osmolar Concentration
Phosphodiesterase Inhibitors / pharmacology
Physical Conditioning, Animal*
Rats
Rats, Sprague-Dawley
Time Factors
Trichloroacetic Acid
Grant Support
ID/Acronym/Agency:
R01-AR-19393/AR/NIAMS NIH HHS
Chemical
Reg. No./Substance:
0/Phosphodiesterase Inhibitors; 60-92-4/Cyclic AMP; 64-17-5/Ethanol; 76-03-9/Trichloroacetic Acid; 7683-59-2/Isoproterenol
Investigator
Investigator/Affiliation:
C R Kirby / U TX Med Sch, Houston; F W Booth / U TX Med Sch, Houston

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Single-channel characteristics of a purified bovine renal amiloride-sensitive Na+ channel in planar ...
Next Document:  Increases in human skeletal muscle Na(+)-K(+)-ATPase concentration with short-term training.