Document Detail

The burden of disease of retinal vein occlusion: review of the literature.
MedLine Citation:
PMID:  21546916     Owner:  NLM     Status:  MEDLINE    
Retinal vein occlusion (RVO) is the second most common cause of vision loss due to retinal vascular disease. A literature review was undertaken to understand the epidemiology, clinical consequence, current practice patterns, and cost of RVO. Pertinent articles were identified by computerized searches of the English language literature in MEDLINE supplemented with electronic and manual searches of society/association proceedings and bibliographies of electronically identified sources. Population-based studies report a prevalence rate of 0.5-2.0% for branch RVO and 0.1-0.2% for central RVO. The 15-year incidence rate is estimated to be 1.8% for branch RVO and 0.2% for central RVO. Patients with RVO report lower vision-related quality of life than those without ocular disease. Available treatment options are limited. Until recently there was no treatment for central RVO. Laser photocoagulation is only recommended for branch RVO in patients who have not experienced severe vision loss. Emerging evidence on the effectiveness of intravitreal anti-vascular endothelial growth factor therapy and dexamethasone intravitreal implant is promising. Information on the treatment patterns and cost of RVO is extremely limited with one retrospective analysis of secondary insurance payment data identified and limited to the United States population only. A better understanding of the economic and societal impact of RVO will help decision makers evaluate emerging medical interventions for this sight-threatening disease.
M Laouri; E Chen; M Looman; M Gallagher
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2011-05-06
Journal Detail:
Title:  Eye (London, England)     Volume:  25     ISSN:  1476-5454     ISO Abbreviation:  Eye (Lond)     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-08-11     Completed Date:  2011-10-20     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  8703986     Medline TA:  Eye (Lond)     Country:  England    
Other Details:
Languages:  eng     Pagination:  981-8     Citation Subset:  IM    
Health Economics and Outcomes, Quorum Consulting Inc., San Francisco, CA 94104-3716, USA.
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MeSH Terms
Aged, 80 and over
Cost of Illness
Light Coagulation / economics
Middle Aged
Retinal Vein Occlusion* / economics,  epidemiology,  therapy
Tomography, Optical Coherence / economics
Vision Disorders / economics,  etiology,  therapy

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