Document Detail


The 'buoy' stent: evaluation of a prototype indwelling ureteric stent in a porcine model.
MedLine Citation:
PMID:  19154469     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE To assess a prototype ureteric 'buoy' stent with a 10 F upper body tapering to a 3F tail, developed to potentially reduce stent-related irritative symptoms while providing an adequate mould for healing after endopyelotomy. MATERIALS AND METHODS Eighteen Yucatan minipigs had the stent placed either into the intact ureter (phase I) or after Acucise proximal endoureterotomy (phase II). Buoy stents were compared to 10/7 F endopyelotomy stents and to standard 7 F stents in phases I and II, respectively. The pigs were assessed for vesico-ureteric reflux, hydronephrosis and infection, before stent insertion and at harvest. Stents were weighed before and after placement and the removal force was measured. Pressure/flow studies, antegrade nephrostograms and specimens for histopathology from the renal pelvis, ureter and vesico-ureteric junction (VUJ) were obtained at harvest. RESULTS Thirteen minipigs survived the entire study. Ureteric flow with the stents in situ was better for buoy stents than for 10/7 F stents (P < 0.005). Ureteric flow after endoureterotomy and subsequent stent removal was similar for buoy stents and standard 7 F stents. None of the stents refluxed. There was no difference between stents in removal force, weight change or incidence of hydronephrosis. At 1 and 12 weeks, buoy stents tended to produce lower histopathological alteration scores than control stents, especially at the VUJ (phase I, 2.0 vs 3.9, P = 0.092; phase II, 0.6 vs 1.7, P = 0.18). CONCLUSIONS The novel buoy stents are easily placed and removed via the urethra. They can cause less VUJ inflammation than standard stents while allowing for adequate ureteric flow and healing after proximal endoureterotomy.
Authors:
Alfred Krebs; Leslie A Deane; James F Borin; Robert A Edwards; Leandro G Sala; Farhan Khan; Corollos Abdelshehid; Elspeth M McDougall; Ralph V Clayman
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article     Date:  2009-01-14
Journal Detail:
Title:  BJU international     Volume:  104     ISSN:  1464-410X     ISO Abbreviation:  BJU Int.     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-08-03     Completed Date:  2009-09-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100886721     Medline TA:  BJU Int     Country:  England    
Other Details:
Languages:  eng     Pagination:  88-92     Citation Subset:  IM    
Affiliation:
Department of Urology, University of California, Irvine Medical Center, Orange, CA, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Device Removal
Equipment Design
Female
Hydronephrosis / prevention & control*
Stents / microbiology,  standards*
Swine
Swine, Miniature
Ureter / microbiology,  pathology,  surgery*
Urinary Tract Infections / prevention & control*
Vesico-Ureteral Reflux / prevention & control*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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