Document Detail

The brockenbrough - braunwald - morrow sign.
MedLine Citation:
PMID:  24932361     Owner:  NLM     Status:  In-Data-Review    
Hypertrophic cardiomyopathy is a relatively common genetic disorder and usually asymptomatic. However, approximately 25% of patients develop left ventricular outflow obstruction and can develop angina, syncope, or congestive heart failure. Initiation and titration of beta-blockade usually results in symptomatic improvement. Patients with medically refractory symptoms can see further symptomatic improvement and relief of obstruction with either surgical myectomy or alcohol septal ablation (ASA). Although surgical myectomy has been the gold standard, ASA has been shown in nonrandomized studies and a meta-analysis to be comparable. In patients undergoing ASA without a rest obstruction, the Brokenbrough-Braunwald-Morrow sign can be used to accurately determine the degree of left ventricular outflow tract (LVOT) obstruction prior to, during, and after ASA.
Alejandro R Trevino; John Buergler
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Methodist DeBakey cardiovascular journal     Volume:  10     ISSN:  1947-6108     ISO Abbreviation:  Methodist Debakey Cardiovasc J     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2014-06-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101508600     Medline TA:  Methodist Debakey Cardiovasc J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  34-7     Citation Subset:  IM    
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