Document Detail

The brain in healthy aged individuals: MR imaging.
MedLine Citation:
PMID:  2305048     Owner:  NLM     Status:  MEDLINE    
Twenty-four healthy aged individuals with above-average intellectual function were studied with use of a low-field-strength (0.02-T) magnetic resonance (MR) imager. The group was carefully selected so as not to include persons with signs of arteriosclerotic diseases, major somatic disease, or a history of brain disease or dementia in the family. The width of the subarachnoid spaces and lateral ventricles, as well as the frequency and degree of brain white-matter lesions, were described with the use of a visual rating scale. White matter lesions were found in less than 9% of the subjects. The lateral brain ventricles were enlarged in 8% of all individuals and the cortical cerebrospinal fluid (CSF) spaces in more than 40% of all individuals. Moreover, T1 and T2 were estimated in different brain areas, and a positive correlation between T1 in the frontal white matter and age was found. A computer-assisted classification procedure was used to estimate brain tissue and CSF areas. The results of this procedure strongly correlated with the visually estimated ventricular size.
L O Wahlund; I Agartz; O Almqvist; H Basun; L Forssell; J Sääf; L Wetterberg
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  174     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1990 Mar 
Date Detail:
Created Date:  1990-03-27     Completed Date:  1990-03-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  675-9     Citation Subset:  AIM; IM    
Karolinska Institute, Department of Psychiatry, St Göran's Hospital, Stockholm, Sweden.
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MeSH Terms
Aged, 80 and over
Aging / pathology*
Brain / anatomy & histology*
Cerebral Ventricles / anatomy & histology
Image Processing, Computer-Assisted
Intelligence Tests
Magnetic Resonance Imaging

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