Document Detail

The brain in congestive heart failure.
MedLine Citation:
PMID:  15374144     Owner:  NLM     Status:  PubMed-not-MEDLINE    
In the present paper we discuss two issues about relationships between congestive heart failure and the brain. First, major acute cerebrovascular events are very frequent among elderly people, but stroke does not appear to be frequently associated with congestive heart failure. Second, some cardiovascular conditions may determine progressive damage of cerebral tissue, with consequent impairment of cognitive functions. The association of cognitive impairment and cardiovascular diseases may dramatically increase morbility and mortality risks in the elderly. Recent studies seem to show that hypotension and congestive heart failure are risk factors for dementia in elderly people. In view of this data, an Italian multicentric study on congestive heart failure in hospitalized elderly patients (CHF Italian Study I) included a brief screening of cognitive abilities (MMSE). The presence of congestive heart failure induced a significant decrease of MMSE scores: mean MMSE score after statistical adjustment for the other variables was about one point lower in patients with congestive heart failure respect to elderly patients affected by heart disease but without congestive heart failure. A novel multicentric study (CHF Italian Study II) has been performed to identify cognitive functions more specifically impaired during congestive heart failure in the elderly. Preliminary data relative to 385 patients, confirmed that congestive heart failure may induce a generalized impairment of cognitive functions. These data have relevant clinical implications because they demonstrate that a multidisciplinary approach is necessary in these patients, both for prevention and rehabilitation therapy.
D Acanfora; L Trojano; G L Iannuzzi; G Furgi; C Picone; C Rengo; P Abete; F Rengo;
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of gerontology and geriatrics     Volume:  23     ISSN:  0167-4943     ISO Abbreviation:  Arch Gerontol Geriatr     Publication Date:    1996 Nov-Dec
Date Detail:
Created Date:  2004-09-17     Completed Date:  2005-03-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8214379     Medline TA:  Arch Gerontol Geriatr     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  247-56     Citation Subset:  -    
Salvatore Maugeri Foundation, Institute of Care and Scientific Research, Rehabilitation Institute of Campoli del Monte Taburno, Via N. Bixio, 10-82030 Benevento, Italy.
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