| Is blood versus crystalloid cardioplegia relevant? Significantly improved protection may require new cardioplegic concepts! | |
| | |
MedLine Citation:
|
PMID: 18784121 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The predominant method of myocardial protection during cardiac surgery is hyperkalaemic cardioplegia, inducing depolarised arrest. Since its development in the 1970s, the only real change has been to alter the vehicle to blood. Although blood cardioplegia was shown to be 'superior' to crystalloid cardioplegia, this advantage is marginal and might explain the continuous use of crystalloid cardioplegia by some surgeons. To achieve significant improvements in cardioplegic protection, more radical and conceptual changes in the solution, such as those potentially achieved by 'polarised' arrest, should be explored. |
| | |
Authors:
|
Hazem B Fallouh; David J Chambers |
Publication Detail:
|
Type: Comparative Study; Journal Article Date: 2008-09-10 |
Journal Detail:
|
Title: Interactive cardiovascular and thoracic surgery Volume: 7 ISSN: 1569-9285 ISO Abbreviation: Interact Cardiovasc Thorac Surg Publication Date: 2008 Dec |
Date Detail:
|
Created Date: 2008-11-25 Completed Date: 2009-01-29 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101158399 Medline TA: Interact Cardiovasc Thorac Surg Country: England |
Other Details:
|
Languages: eng Pagination: 1162-3 Citation Subset: IM |
Affiliation:
|
Cardiac Surgical Research/Cardiothoracic Surgery, The Rayne Institute King's College London, Guy's and St Thomas' NHS Foundation Trust, St Thomas' Hospital, London, UK. hazem.fallouh@kcl.ac.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cardiac Surgical Procedures
/
adverse effects* Cardioplegic Solutions / therapeutic use* Heart Arrest, Induced / methods* Humans Myocardial Reperfusion Injury / etiology, prevention & control* Potassium Compounds / therapeutic use* Practice Guidelines as Topic |
| Chemical | |
Reg. No./Substance:
|
0/Cardioplegic Solutions; 0/Potassium Compounds; 0/potassium cardioplegic solution |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Can estimated glomerular filtration rate improve the EuroSCORE?
Next Document: Sympathetic and sensory nerve activation during negative pressure therapy of sternotomy wounds.