| On the blood group B gene-specified alpha-galactosyltransferase in the serum of the Japanese tortoise (Clemmys japonica). | |
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MedLine Citation:
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PMID: 977033 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Human blood group O cells were converted into B-active cells by incubation at either 4 degrees or 37 degrees with uridine diphosphate D-galactose and unfractionated serum from the Japanese tortoise (Clemmys japonica). The specificity of the converted cells was tested by their reactions with human anti-B, anti-A and rabbit anti-B sera. Under the conditions used, Bombay (Oh) type cells were not converted, and group-O foetal cells possessing a few H antigenic sites were only weakly converted into B-active cells. In addition, the agglutination titre of the converted cells with eel anti-H serum decreased. These results therefore indicate that the conversion depends upon the preference of H-substance on the red cells. The alpha-galactosyltransferase in tortoise serum thus resembles the transferase in human group-B serum and these results suggest that the mechanism of biosynthesis of blood group B substance in the tortoise is similar to that in humans. |
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Authors:
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Y Matsukura |
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Publication Detail:
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Type: In Vitro; Journal Article |
Journal Detail:
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Title: Immunology Volume: 31 ISSN: 0019-2805 ISO Abbreviation: Immunology Publication Date: 1976 Oct |
Date Detail:
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Created Date: 1976-12-23 Completed Date: 1976-12-23 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0374672 Medline TA: Immunology Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 571-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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ABO Blood-Group System* Animals Erythrocytes / enzymology Galactosyltransferases / blood* Hemagglutination Tests Humans Time Factors Turtles / blood* Uridine Diphosphate Galactose |
| Chemical | |
Reg. No./Substance:
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0/ABO Blood-Group System; 2956-16-3/Uridine Diphosphate Galactose; EC 2.4.1.-/Galactosyltransferases |
| Comments/Corrections | |
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