| A 'black cornea' secondary to topical epinephrine. | |
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MedLine Citation:
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PMID: 974858 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a case of 'black cornea" secondary to topical epinephrine therapy and present the biochemical analysis of the lesion. The formed pigment is a melanin and not the intermediate substance, adrenochrome, as has been previously reported. The pathogenesis of melanin deposition is reviewed and a hypothesis of epinephrine-melanin binding is suggested. |
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Authors:
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R W McCarthy; R LeBlanc |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Volume: 11 ISSN: 0008-4182 ISO Abbreviation: Can. J. Ophthalmol. Publication Date: 1976 Oct |
Date Detail:
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Created Date: 1977-01-03 Completed Date: 1977-01-03 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0045312 Medline TA: Can J Ophthalmol Country: CANADA |
Other Details:
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Languages: eng Pagination: 336-40 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cornea
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metabolism* Corneal Diseases / chemically induced*, metabolism, pathology Epinephrine / adverse effects*, metabolism, therapeutic use Female Glaucoma / drug therapy Humans Melanins / metabolism* Middle Aged Ophthalmic Solutions |
| Chemical | |
Reg. No./Substance:
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0/Melanins; 0/Ophthalmic Solutions; 51-43-4/Epinephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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