Document Detail


The biotransformation of aromatic amino acids by Phoma macrostoma.
MedLine Citation:
PMID:  20184027     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A search for natural products produced in fermentation cultures of a strain of Phoma macrostoma led to the identification of tyrosol as the major metabolite produced by this organism. The addition of the amino acid tyrosine to growing fermentation cultures of P. macrostoma resulted in an increase in the production of tyrosol. It was subsequently determined that this strain of P. macrostoma was also capable of the biotransformation of other amino acids into similar alcohols.
Authors:
Yevgeniya Tyagunova; John L Sorensen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Natural product communications     Volume:  5     ISSN:  1934-578X     ISO Abbreviation:  Nat Prod Commun     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-02-26     Completed Date:  2010-04-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101477873     Medline TA:  Nat Prod Commun     Country:  United States    
Other Details:
Languages:  eng     Pagination:  81-4     Citation Subset:  IM    
Affiliation:
Department of Chemistry, University of Manitoba, 144 Dysart Road, Winnipeg, MB, R3T 2N2, Canada.
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MeSH Terms
Descriptor/Qualifier:
Amino Acids, Aromatic / metabolism*
Ascomycota / metabolism*
Biotransformation
Chemical
Reg. No./Substance:
0/Amino Acids, Aromatic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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