| The biomimetic immunoassay based on molecularly imprinted polymer: a comprehensive review of recent progress and future prospects. | |
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MedLine Citation:
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PMID: 21535786 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Immunoassay, based on a selective affinity of the biological antibody for its antigen, is one of the most usual analytical methods in food safety and environmental chemistry. However, it presents several drawbacks because of the nature of the antibody. Molecular imprinting technique, due to its high selectivity and stability, ease of preparation and low cost, has shown great potential in producing artificial antibodies in biomimetic immunoassays. This article focuses on the recent states, advantages, current problems and outlooks of molecularly imprinted radio, fluoro, enzyme-linked and chemiluminescent immunoassays, and biomimetic immunosensor, with special emphasis on the challenges in developing biomimetic enzyme-linked immunosorbent assays (BELISAs). The biomimetic immunoassay method will provide an important new analysis platform in food safety, although the sensitivity and specificity is relatively low. Practical Application: As a new simple analysis method, the biomimetic immunoassay has attractive prospect, although some limitations were existed in real-sample assay. In this critical review, some promising solutions for overcoming its drawbacks were put forward, which may promote the more quick development and extensive application of this method in food safety. |
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Authors:
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Z X Xu; H J Gao; L M Zhang; X Q Chen; X G Qiao |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of food science Volume: 76 ISSN: 1750-3841 ISO Abbreviation: J. Food Sci. Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-05-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0014052 Medline TA: J Food Sci Country: United States |
Other Details:
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Languages: eng Pagination: R69-75 Citation Subset: IM |
Affiliation:
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Authors Xu, Zhang, Chen, and Qiao are with College of Food Science and Engineering, Shandong Agricultural Univ., Taian 271018, China. Author Gao is with College of Forestry, Shandong Agricultural Univ., Taian 271018, China. Direct inquiries to author Qiao (E-mail: xgqiao@sdau.edu.cn). |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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