Document Detail


A biomechanical and histological analysis of standard versus hydroxyapatite-coated pins for external fixation.
MedLine Citation:
PMID:  18286593     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This sheep study was designed to make a comparative evaluation of two external fixation pin types each with and without hydroxyapatite (HA) coating. The two pins had different taper, pitch, and self drilling capabilities. Twenty Orthofix standard, self-tapping pins (group A), 20 Orthofix HA-coated, self-tapping pins (group B), 20 X-caliber, self-drilling, self-tapping pins (group C), and 20 X-caliber HA-coated, self-drilling, self-tapping pins (group D) were selected. Four pins were implanted in the right femurs of 20 adult sheep that were euthanized at 6 weeks. Mean pin insertion torque was 2745 +/- 822 Nmm in group A, 2726 +/- 784 Nmm in group B, 2818 +/- 552 Nmm in group C, and 2657 +/- 732 Nmm in group D (ns). Mean pin extraction torque was 1567 +/- 541 Nmm in group A, 2524 +/- 838 Nmm in group B, 1650 +/- 650 Nmm in group C, and 2517 +/- 726 Nmm in group D. HA-coated pins (group B and D) had a significantly greater mean pin extraction torque compared to similar uncoated pins (group A and C) (p < 0.0005). Histological analysis showed good osteointegration of the two coated pin types. This study shows that HA-coating is more important for optimal pin fixation than the particular combination of design parameters used in each pin type.
Authors:
Antonio Moroni; Matteo Cadossi; Matteo Romagnoli; Cesare Faldini; Sandro Giannini
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of biomedical materials research. Part B, Applied biomaterials     Volume:  86     ISSN:  1552-4981     ISO Abbreviation:  J. Biomed. Mater. Res. Part B Appl. Biomater.     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-16     Completed Date:  2008-09-17     Revised Date:  2011-09-26    
Medline Journal Info:
Nlm Unique ID:  101234238     Medline TA:  J Biomed Mater Res B Appl Biomater     Country:  United States    
Other Details:
Languages:  eng     Pagination:  417-21     Citation Subset:  IM    
Copyright Information:
(c) 2007 Wiley Periodicals, Inc.
Affiliation:
Rizzoli Orthopaedic Institute, University of Bologna, Bologna, Italy. a.moroni@ior.it
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MeSH Terms
Descriptor/Qualifier:
Animals
Biomechanics
Bone Nails*
Coated Materials, Biocompatible / chemistry*
Durapatite*
Equipment Design
External Fixators*
Femur / surgery
Materials Testing
Sheep
Chemical
Reg. No./Substance:
0/Coated Materials, Biocompatible; 1306-06-5/Durapatite

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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