| The biology of interleukin-1: emerging concepts in the regulation of the actin cytoskeleton and cell junction dynamics. | |
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MedLine Citation:
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PMID: 21744066 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Interleukin (IL)-1 is a proinflammatory cytokine with important roles in innate immunity, as well as in normal tissue homeostasis. Interestingly, recent studies have also shown IL-1 to function in the dynamics of the actin cytoskeleton and cell junctions. For example, treatment of different epithelia with IL-1α often results in the restructuring of the actin network and cell junctions, thereby leading to junction disassembly. In this review, we highlight new and interesting findings that show IL-1 to be a critical player of restructuring events in the seminiferous epithelium of the testis during spermatogenesis. |
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Authors:
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Pearl P Y Lie; C Yan Cheng; Dolores D Mruk |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-9 |
Journal Detail:
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Title: Cellular and molecular life sciences : CMLS Volume: - ISSN: 1420-9071 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-7-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9705402 Medline TA: Cell Mol Life Sci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Center for Biomedical Research, Population Council, 1230 York Avenue, New York, NY, 10065, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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