Document Detail

The biology of cadmium.
MedLine Citation:
PMID:  775217     Owner:  NLM     Status:  MEDLINE    
Industrial exposure to large amounts of cadmium is known to be toxic to man; however, the low levels of cadmium in water, food, and air to which everyone is continually exposed have no obvious effects. During childhood and adolescence, ingestion and inhalation of cadmium are responsible for the average American accumulating about 30 mg of cadmium in his body, with the highest concentration being in the kidney. It has been suggested on the basis of two observations that elevated renal cadmium might be associated with essential hypertension: (1) Hypertensives have been reported to have higher renal cadmium concentrations than normotensives. (2) Long-term exposure to low levels of cadmium has reproducibly caused mild hypertension in animals. Finally, increased levels of cadmium have been found in lungs and other tissues of emphysematous subjects.
H M Perry; G S Thind; E F Perry
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review    
Journal Detail:
Title:  The Medical clinics of North America     Volume:  60     ISSN:  0025-7125     ISO Abbreviation:  Med. Clin. North Am.     Publication Date:  1976 Jul 
Date Detail:
Created Date:  1976-08-02     Completed Date:  1976-08-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985236R     Medline TA:  Med Clin North Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  759-69     Citation Subset:  IM    
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MeSH Terms
Air Pollutants
Cadmium / metabolism,  pharmacology*
Child, Preschool
Dose-Response Relationship, Drug
Emphysema / chemically induced
Environmental Exposure
Food Contamination
Hypertension / chemically induced
Kidney / metabolism
Middle Aged
Occupational Diseases / chemically induced
Poisoning / etiology,  metabolism
United States
Water Pollutants, Chemical
Reg. No./Substance:
0/Air Pollutants; 0/Water Pollutants, Chemical; 7440-43-9/Cadmium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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