Document Detail

The biochemistry of natural fasting at its limits.
MedLine Citation:
PMID:  1612138     Owner:  NLM     Status:  MEDLINE    
There are several groups of animals that are adapted for extremely long duration fasting as part of their reproductive cycle. Penguins, bears and seals routinely fast without food or water for months at time. However, they do not 'starve', as the biochemical implications of starving are very different from those of successful fasting. There are distinct biochemical adaptations in lipid, carbohydrate and especially protein metabolism that allow these animals to survive. It appears, at least for penguins and seals, that the duration of the fast may be limited by changes that occur in biochemical regulation near the ned of the fast. In all of these species, the biochemistry of fasting and the ecological and behavioral demands of their breeding cycles are closely interrelated.
M A Castellini; L D Rea
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Experientia     Volume:  48     ISSN:  0014-4754     ISO Abbreviation:  Experientia     Publication Date:  1992 Jun 
Date Detail:
Created Date:  1992-07-30     Completed Date:  1992-07-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376547     Medline TA:  Experientia     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  575-82     Citation Subset:  IM    
Institute of Marine Science, University of Alaska, Fairbanks 99775.
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MeSH Terms
Birds / metabolism
Blood Urea Nitrogen
Fasting / physiology*
Fatty Acids, Nonesterified / blood
Hydroxybutyrates / blood
Seals, Earless / metabolism
Ursidae / metabolism
Reg. No./Substance:
0/Fatty Acids, Nonesterified; 0/Hydroxybutyrates

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