Document Detail


A biocatalytic hydrogenation of carboxylic acids.
MedLine Citation:
PMID:  23139934     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The hyperthermophile Pyrococcus furiosus catalyses the hydrogenation of a broad range of carboxylic acids selectively to the corresponding primary alcohols. Other functional groups such as isolated C[double bond, length as m-dash]C-double bonds are not touched. The chemoselectivity of the carboxylate reduction may be directed towards aldehydes by simple medium engineering.
Authors:
Yan Ni; Peter-Leon Hagedoorn; Jian-He Xu; Isabel W C E Arends; Frank Hollmann
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-9
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Delft University of Technology, Department of Biotechnology, Julianalaan 136, 2628BL Delft, The Netherlands. p.l.hagedoorn@tudelft.nl f.hollmann@tudelft.nl.
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