Document Detail

A benign metastasizing leiomyoma involving a nodule in the pulmonary artery: case and literature review.
MedLine Citation:
PMID:  21077481     Owner:  NLM     Status:  MEDLINE    
Benign metastasizing leiomyoma (BML) is a rare disease defined as a primary benign uterine tumor with "metastatic" lesions preferentially occurring in the lung, pelvis and lymph nodes. There are few reports about local recurrence after initial surgery. We report a case of a BML with local recurrence and metastasis growing into the wall of the left pulmonary artery, diagnosed 11 years after initial hysterectomy. A 55-year-old woman complaining of abdominal discomfort, heaviness and asthenia was admitted to our hospital for investigation of a voluminous uterine mass with high vascularization and three pulmonary nodules. The resection of the mass by laparotomy was complicated by uncontrolled severe hemorrhage due to vascular proliferation, requiring multiple transfusions, packing the cavity and postoperative uterine artery embolization. Three months later the patient underwent a left upper lobe lobectomy with the aim of removing the largest pulmonary nodule, a nodule a located in the lingular branch of the left pulmonary artery. The comparison of hysterectomy and lobectomy pieces showed a similar aspect, leading thus to the diagnosis of BML. Awareness of this rare entity should potentially avoid under-diagnosis and difficulties due to hemorrhage during surgery.
O Poujade; A S Genin; M Dhouha; D Luton
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  European journal of gynaecological oncology     Volume:  31     ISSN:  0392-2936     ISO Abbreviation:  Eur. J. Gynaecol. Oncol.     Publication Date:  2010  
Date Detail:
Created Date:  2010-11-16     Completed Date:  2010-12-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8100357     Medline TA:  Eur J Gynaecol Oncol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  329-32     Citation Subset:  IM    
Obstetrics and Gynecology Department, Beaujon Hospital, Clichy France.
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MeSH Terms
Leiomyoma / pathology*
Lung Neoplasms / secondary*
Middle Aged
Pulmonary Artery / pathology*
Uterine Neoplasms / pathology*

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