| The benefit of expiratory-phase quantitative CT densitometry in the early diagnosis of chronic obstructive pulmonary disease. | |
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MedLine Citation:
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PMID: 22261851 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE: We aimed to compare the inspiratory and expiratory quantitative computed tomography (CT) densitometric data of healthy volunteers, individuals with chronic obstructive pulmonary disease (COPD) risk, and COPD patients to aid in the early diagnosis of COPD. MATERIALS AND METHODS: Of the study patients, 14 were healthy volunteers (Group I), 12 were patients at risk for COPD (Group II), and 13 were COPD patients (Group III). The high-resolution CT was performed at three levels (the upper, middle, and lower parts of the lungs). All images were evaluated with a specific program for the segmentation of pulmonary parenchyma. The mean lung density (MLD) was measured, and the emphysema index (EI) was calculated using this program. RESULTS: Both MLD values and calculated EI ratios showed significant differences between Groups I and III, and Groups II and III in both expiratory and inspiratory phases (P < 0.05). However, in the comparison of healthy volunteers and patients at risk for COPD (Group I and II), only expiratory-phase MLD values showed statistically significant difference (P < 0.001). CONCLUSION: MLD and calculated EI ratios showed significant difference between healthy volunteers and COPD patients. In patients at risk for COPD, expiratory-phase MLD measurements can be used as an early diagnostic method. |
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Authors:
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Fahri Halit Besir; Kamran Mahmutyazicioglu; Leyla Aydin; Remzi Altin; Kiyasettin Asil; Sadi Gundogdu |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-19 |
Journal Detail:
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Title: Diagnostic and interventional radiology (Ankara, Turkey) Volume: - ISSN: 1305-3612 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101241152 Medline TA: Diagn Interv Radiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Radiology, Duzce University School of Medicine, Duzce, Turkey. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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