| The behavior of mucopolysaccharide in the pancreatic juice in chronic pancreatitis. | |
| | |
MedLine Citation:
|
PMID: 952274 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
In order to study whether or not mucosubstance increases occur in the pancreatic juice of patients with chronic pancreatitis, hexosamine was measured in duodenal aspirates during the secretin phase (S-40) following pancreozymin-secretin stimulation in 16 normal subjects, 37 patients with chronic pancreatitis, 6 patients with alcoholism, 13 patients with gallstones, and 11 patients with peptic ulcer. The hexosamine concentrations in the pancreatic secretions showed a negative correlation with the bicarbonate concentrations and volume output. Rises in hexosamine concentration were seen in alcoholism and chronic pancreatitis, especially in alcoholic pancreatitis. This is probably intimately related with the repeated ingestion of large amounts of alcohol over long periods of time. Since high hexosamine values are noted in the relapsing type of chronic alcoholic pancreatitis, increases in viscosity due to mucosubstance increases in the pancreatic juice are probably related with the recurrence of acute attacks accompanying ductal stenosis or obstruction. |
| | |
Authors:
|
A Wakabayashi; Y Takeda |
Related Documents
:
|
8119544 - Serum levels of pancreatitis-associated protein as indicators of the course of acute pa... 2122444 - Serum apolipoprotein a-i in alcoholic patients with chronic calcifying pancreatitis. 11803494 - Asymptomatic elevation of serum lipase and amylase in conjunction with crohn's disease ... 10834684 - Exocrine pancreatic function in critically ill patients: septic shock versus non-septic... 18473114 - Administration off label of recombinant factor-viia (rfviia) to patients with blunt or ... 3699544 - Lithium fluxes across the gastric mucosa after truncal vagotomy and drainage--an object... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The American journal of digestive diseases Volume: 21 ISSN: 0002-9211 ISO Abbreviation: Am J Dig Dis Publication Date: 1976 Aug |
Date Detail:
|
Created Date: 1976-10-02 Completed Date: 1976-10-02 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0404011 Medline TA: Am J Dig Dis Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 607-12 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Alcoholism
/
complications Amylases / metabolism Bicarbonates / metabolism Cholecystokinin / pharmacology Chronic Disease Duodenum / metabolism Hexosamines / metabolism* Humans Pancreatic Juice / enzymology, metabolism* Pancreatitis / etiology, metabolism* Proteins / metabolism Secretin / pharmacology Stimulation, Chemical |
| Chemical | |
Reg. No./Substance:
|
0/Bicarbonates; 0/Hexosamines; 0/Proteins; 1393-25-5/Secretin; 9011-97-6/Cholecystokinin; EC 3.2.1.-/Amylases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Esophageal dysfunction and Raynaud's phenomenon in patients with scleroderma.
Next Document: A bioptic study of gastrointestinal mucosa in cholera patients during an epidemic in southern Italy.