Document Detail

The basis for setting the upper range of adequate intake for regulation of macronutrient intakes, especially amino acids.
MedLine Citation:
PMID:  15173441     Owner:  NLM     Status:  MEDLINE    
The comparison of actual intakes of essential amino acids to the dietary reference intakes indicates that amino acid supply is likely not a public health concern in industrialized countries. This fact does not preclude the interest in specific amino acid intake in some physiological or pathological situations in targeted subgroups of the population. Thus, the addition of amino acids to some food vehicles to create functional foods will be regulated by public authorities in different ways according to the regulatory contexts specific to each country. The main issues to be considered are, however, the same: safety of the product and justification of the health claim accompanying the product's promotion. In addition to classical scientific data, the use of Monte Carlo simulations can be a useful tool to support the choice of the food vehicle and the amounts added to this food, and to demonstrate both safety and possible efficacy of the functional food in the targeted population.
Ambroise Martin; Mathilde Touvier; Jean-Luc Volatier
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of nutrition     Volume:  134     ISSN:  0022-3166     ISO Abbreviation:  J. Nutr.     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-06-02     Completed Date:  2004-07-08     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0404243     Medline TA:  J Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1625S-1629S; discussion 1630S-1632S, 1667S-1672S     Citation Subset:  IM    
Direction of Risk Assessment for Nutrition and Food Safety, French Food Safety Agency, 94701 Maisons-Alfort Cedex, France.
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MeSH Terms
Amino Acids / administration & dosage*
Computer Simulation
Health Food
Health Policy
Monte Carlo Method
Nutrition Policy
Nutritional Requirements
Nutritional Status*
Reg. No./Substance:
0/Amino Acids

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