Document Detail

The basal plasma membrane and lamina densa of uterine epithelial cells are both altered during early pregnancy and by ovarian hormones in the rat.
MedLine Citation:
PMID:  8534579     Owner:  NLM     Status:  MEDLINE    
Changes in the basal plasma membrane and lamina densa of uterine epithelial cells have been studied in the rat during early pregnancy and under the influence of progesterone and oestrogen. Both the basal plasma membrane and lamina densa become increasingly tortuous by day 6 of pregnancy and this condition is found to be predominantly influenced by progesterone. Oestrogen, either alone or in combination with progesterone, has a much lesser effect. The lamina densa increases in thickness by day 6 of pregnancy and again progesterone is found to have the major influence. These alterations are discussed in the context of implantation of the blastocyst and we highlight the differing effect that ovarian hormones have on different regions of the plasma membrane of uterine epithelial cells.
Y L Shion; C R Murphy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of morphology     Volume:  33     ISSN:  0924-3860     ISO Abbreviation:  Eur J Morphol     Publication Date:  1995 Jul 
Date Detail:
Created Date:  1996-02-06     Completed Date:  1996-02-06     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  9011462     Medline TA:  Eur J Morphol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  257-64     Citation Subset:  IM    
Department of Anatomy and Histology, University of Sydney, NSW Australia.
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MeSH Terms
Cell Membrane / drug effects,  ultrastructure
Epithelial Cells
Epithelium / drug effects,  ultrastructure
Estrogens / pharmacology*
Microscopy, Electron
Pregnancy, Animal / physiology*
Progesterone / pharmacology*
Rats, Wistar
Uterus / cytology,  drug effects,  ultrastructure*
Reg. No./Substance:
0/Estrogens; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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