| Beta-blocker therapy for patients with ventricular heart failure and reduced systolic function. | |
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MedLine Citation:
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PMID: 19667666 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Approximately 5 million people in the United States are living with heart failure. The prevalence of heart failure is increasing as the mean age of the population of the US increases. Prognosis is poor: About half of all patients who have heart failure die within 5 years of onset. Management of heart failure has 3 major goals: (1) the specific treatment of the underlying cardiac disease; (2) relief of symptoms and improvement of quality of life; and (3) modification of the long-term neurohormonal progression. From clinical trial data, beta-blockers are recommended in national heart failure management guidelines as part of the standard therapy, along with diuretics, angiotensin-converting enzyme (ACE) inhibitors, and (usually) digoxin. Other agents such as angiotensin II-receptor blockers and mineralocorticoid (aldosterone) receptor antagonists may also be important. |
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Authors:
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Thomas D Giles |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Postgraduate medicine Volume: 114 ISSN: 1941-9260 ISO Abbreviation: Postgrad Med Publication Date: 2003 Dec |
Date Detail:
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Created Date: 2009-08-11 Completed Date: 2009-09-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401147 Medline TA: Postgrad Med Country: United States |
Other Details:
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Languages: eng Pagination: 18-29 Citation Subset: AIM; IM |
Affiliation:
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Division of Cardiology, Louisiana State University School of Medicine, New Orleans, LA 70112, USA. tgiles@lsuhsc.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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therapeutic use* Disease Progression Evidence-Based Medicine Heart Failure / drug therapy* Heart Rate / physiology Humans Hypertension / complications Ventricular Dysfunction / drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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