Document Detail


The availability of circulating blood volume values alters fluid management in critically ill surgical patients.
MedLine Citation:
PMID:  19185111     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: This study evaluated whether commercially available blood volume measurements in critically ill surgical patients altered fluid management. METHODS: Patients admitted to the surgical intensive care unit of a tertiary care teaching hospital were prospectively evaluated. The frequency of changes in fluid management when results of blood volume measurements were available was determined. RESULTS: In a pilot study, the frequency of instances when measurement of blood volume would have altered fluid management was statistically significant (P = .0003). In 40 subsequent patients, treatment change occurred in 36% of instances when blood volume results were obtained (P < .001). In the majority, no immediate qualitative change in clinical status occurred, with a desirable clinical response in 39% and no negative treatment responses (P < .001). CONCLUSIONS: Blood volume measurements may assist in the management of critically ill surgical patients by providing a direct measure of intravascular volume. Further studies are warranted to determine its effect on outcome.
Authors:
Danny M Takanishi; Elisabeth N Biuk-Aghai; Mihae Yu; Fedor Lurie; Hideko Yamauchi; Hao C Ho; Alyssa D Chapital; Wega Koss
Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of surgery     Volume:  197     ISSN:  1879-1883     ISO Abbreviation:  Am. J. Surg.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-02-02     Completed Date:  2009-03-04     Revised Date:  2009-05-20    
Medline Journal Info:
Nlm Unique ID:  0370473     Medline TA:  Am J Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  232-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Surgery, University of Hawaii, Honolulu, HI, USA. dtakanis@hawaii.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Volume*
Critical Illness / therapy*
Female
Fluid Therapy*
Humans
Intensive Care
Male
Middle Aged
Pilot Projects
Prospective Studies
Single-Blind Method
Surgical Procedures, Operative

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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