Document Detail

An autopsy case of cardiomyopathy with restrictive physiology in a child.
MedLine Citation:
PMID:  2093718     Owner:  NLM     Status:  MEDLINE    
An autopsy case of cardiomyopathy with restrictive physiology associated with subendocardial myocardial necrosis and fibrosis in a seven-year-old child is described. Cardiac catheterization showed high left ventricular end-diastolic pressure with a dip-and-plateau pattern. Macroscopically, marked dilatation with fibroelastosis in both atria and mild dilatation in both ventricles were observed. Histologic examination revealed extensive subendocardial necrosis with marked disorganization of myocardial cells and moderate arteriolosclerosis. We speculate that these extensive myocardial lesions, which contributed to the restrictive hemodynamic changes, could have been induced by anoxia or a Ca2+ transport abnormality of unknown cause.
M Ishijima; S Kawai; R Okada; T Ino; K Yobuta
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Heart and vessels. Supplement     Volume:  5     ISSN:  0935-736X     ISO Abbreviation:  Heart Vessels Suppl     Publication Date:  1990  
Date Detail:
Created Date:  1991-06-21     Completed Date:  1991-06-21     Revised Date:  2008-02-26    
Medline Journal Info:
Nlm Unique ID:  8810802     Medline TA:  Heart Vessels Suppl     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  70-3     Citation Subset:  IM    
Research Laboratory for Cardiovascular Pathology, Tokyo, Japan.
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MeSH Terms
Cardiomyopathy, Restrictive / complications,  pathology*,  physiopathology*
Coronary Artery Disease / complications
Endomyocardial Fibrosis / complications
Myocardium / pathology*

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