Document Detail

An automatic sutureless coronary anastomotic device: initial results of an animal study.
MedLine Citation:
PMID:  14721812     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The efficacy and long-term patency of a new distal anastomotic device (DAD) for the creation of rapid, sutureless end-to-side venous or arterial coronary artery bypass graft anastomoses were tested in a sheep model. METHODS: The DAD was used on the beating hearts of 34 sheep to create 20 anastomoses between saphenous veins (n = 9) or internal mammary arteries (n = 11) and various coronary arteries. Fourteen conventional hand-sutured anastomoses (7 veins; 7 internal mammary arteries) served as controls. The sheep were sacrificed 1 day, 1 week, and 1, 3, and 6 months after surgery. RESULTS: The immediate patencies of all anastomoses were proven by the rates and pattern of flow. There were no significant differences between the DAD and suture anastomosis groups in presacrifice pulsatility index and occlusion rate. The histomorphometric studies showed complete intimal bridging over the DAD with no significant differences between DAD and suture anastomoses with respect to tissue response, mural injury, inflammation, and adventitial fibrosis. CONCLUSIONS: The DAD enables the creation of rapid, efficient, and sutureless venous or arterial coronary anastomoses. The long-term results of histomorphometric studies show that the results with the DAD are comparable with those of conventional hand-sutured anastomoses.
Yaron Bar-El; Fermin O Tio; Rona Shofti
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The heart surgery forum     Volume:  6     ISSN:  1522-6662     ISO Abbreviation:  Heart Surg Forum     Publication Date:  2003  
Date Detail:
Created Date:  2004-01-14     Completed Date:  2004-05-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100891112     Medline TA:  Heart Surg Forum     Country:  United States    
Other Details:
Languages:  eng     Pagination:  369-74     Citation Subset:  IM    
Department of Cardiac Surgery, Rambam Medical Center, Israel Institute of Technology, Haifa, Israel.
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MeSH Terms
Anastomosis, Surgical / instrumentation,  methods
Coronary Artery Bypass / instrumentation*,  methods
Coronary Vessels / surgery
Equipment Design
Mammary Arteries / transplantation*
Models, Animal
Saphenous Vein / transplantation*
Surgical Instruments*
Suture Techniques
Vascular Patency

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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