| An automated, pre-programmed, multiplexed, hydraulic microvalve. | |
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MedLine Citation:
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PMID: 20024041 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An automated, pre-programmed, multiplexed hydraulic valve actuator is described. The valve is membrane-based and normally open. In contrast to the membrane-based pneumatic valve, the hydraulic valve uses hydraulic liquid to exert the control pressure. The line pressure is controlled with a roller moving over a prefabricated topology. Multiple rollers, each traversing its own track, are assembled into a single carriage, which can be actuated either manually or with a single computer-controlled motor. A valve manifold and roller actuators are designed, fabricated, and tested to demonstrate three-way valve actuation in a pre-determined sequence. The performance of the valve is evaluated and the utility of the valve in the operation of a micro thermal cycler was demonstrated. Hydraulic controllers of the type described here can be operated either manually or under computer control and provide an inexpensive means of controlling flow in lab-on-a-chip devices. |
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Authors:
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Jitae Kim; Dafeng Chen; Haim H Bau |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural Date: 2009-10-12 |
Journal Detail:
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Title: Lab on a chip Volume: 9 ISSN: 1473-0197 ISO Abbreviation: Lab Chip Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-12-21 Completed Date: 2010-01-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101128948 Medline TA: Lab Chip Country: England |
Other Details:
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Languages: eng Pagination: 3594-8 Citation Subset: IM |
Affiliation:
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Department of Mechanical Engineering and Applied Mechanics, University of Pennsylvania, Philadelphia, PA 19104-6315, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Automation DNA / genetics Lab-On-A-Chip Devices* Microfluidic Analytical Techniques Polymerase Chain Reaction Pressure Reproducibility of Results Software* |
| Grant Support | |
ID/Acronym/Agency:
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U01DE017855/DE/NIDCR NIH HHS |
| Chemical | |
Reg. No./Substance:
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9007-49-2/DNA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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