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An audit about labour induction, using prostaglandin, in women with a scarred uterus.
MedLine Citation:
PMID:  22836816     Owner:  NLM     Status:  Publisher    
OBJECTIVES: Induction of labour after a previous caesarean section is still controversial. We aim to analyse, in a population of women who have a uterine scar, the maternal, foetal and neonatal complications in relation to the mode of labour and delivery. STUDY DESIGN: Retrospective analysis of collected data from all the singleton deliveries of patients with a scarred uterus (N = 798), admitted to the hospital between August 2006 and March 2009. Outcomes: maternal and perinatal complications. RESULTS: Among 798 singleton deliveries, 36.1 % had a spontaneous labour, 12.6 % a prostaglandin-induced labour and 2.9 % an ocytocin-induced labour, and 48.4 % had an elective caesarean section. The chance of delivering vaginally was respectively 84.4 % for those who had a spontaneous labour, 75.2 % for those who were induced using prostaglandin, 82.6 % after induction using ocytocin. There were eight uterine ruptures, four after spontaneous labour (1.4 %), two after prostaglandin induction (2 %) and two at the time of an iterative caesarean section (0.5 %). There were no differences between groups, except the risk of haemorrhage (17.4 % after spontaneously induced labour, 34.8 % after ocytocin, 17.8 % after prostaglandin and 44.6 % after iterative caesarean section; p < 0.005) and the neonatal admissions when analysed by intention to treat only (8.3 % after spontaneously induced labour, 9.1 % after ocytocin, 12 % after prostaglandin and 16.8 % after iterative caesarean section; p < 0.009). CONCLUSION: Although no increase in maternal or perinatal outcome was observed in relation to prostaglandin-induced labour after caesarean section, this study is too underpowered to exclude an increased risk.
Alexandra Cogan; Patricia Barlow; Nordine Benali; Daniel Murillo; Yannick Manigart; Julie Belhomme; Serge Rozenberg
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-27
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  -     ISSN:  1432-0711     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Obstetrics and Gynaecology, C.H.U. Saint-Pierre, Université Libre de Bruxelles, Hoog Str 322, 1000, Brussels, Belgium.
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