Document Detail


The attributable burden of hypertension: focus on CKD.
MedLine Citation:
PMID:  21224024     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Hypertension is a worldwide risk factor for premature death and disability from heart disease, stroke, peripheral vascular disease, and kidney failure. Much is known about the role of elevated blood pressure as a contributor to diseases of the heart and brain, but the risk it confers specifically to the development and progression of kidney disease is less well appreciated. The kidney is unique among the target organs of elevated blood pressure because it both suffers damage and still contributes to the pathophysiologic sustenance of hypertension through many avenues. In this overview, we discuss high blood pressure from an epidemiologic standpoint, placing it in a nephrologic perspective and discuss some of the known and speculative mechanisms that link it to kidney damage.
Authors:
Kenneth A Jamerson; Raymond R Townsend
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in chronic kidney disease     Volume:  18     ISSN:  1548-5609     ISO Abbreviation:  Adv Chronic Kidney Dis     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101209214     Medline TA:  Adv Chronic Kidney Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  6-10     Citation Subset:  IM    
Copyright Information:
2011 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.
Affiliation:
University of Michigan Medical Center, Ann Arbor, MI; and Renal Division, University of Pennsylvania, Philadelphia, PA 48106, USA. jamerson@umich.edu
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